Nursing Physiology; genes

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I used our health care informatics system through our clinical library of our HMO to find this article published in Oncogene 2004. Authors: Jose Silva, Kenneth Chang, Gregory Hannon, and Fabiola Rivas. It discussed how sequencing of complete genomes has provided researchers with a wealth of information to genome organization, genetic instability, and knowledge about all potentially expressed genes. The identification of genes encoded in the human genome opens doors for gene silencing by using small interfacing RNAs (siRNA) and short hairpin RNA (shRNA). The application of RNA technology around cancer genes and to delineate molecular pathways in which theses genes affect normal and transformed cells will contribute to the knowledge necessary to develop new and also improve existing cancer therapy.

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